The 1988 Baltimore Orioles finished 7th in the American League East with a record of 54 wins and 107 losses. The season is remembered for the 0-21 start that lasted from April 4 to 28 to start the Orioles season. Manager Cal Ripken, Sr. was fired after an 0-6 start and replaced by Hall of Famer Frank Robinson. The Orioles won their first game of the year against the Chicago White Sox at Comiskey Park on April 29.

This Rawlings official American League baseball was signed by 19 members of the 1988 Orioles. Signatures include:

Don Aase, Mike Boddicker, John Habyan, Tom Niedenfuer, Dave Schmidt, Jay Tibbs, Terry Kennedy, Eddie Murray, Bill Ripken, Cal Ripken, Jr., Rick Schu, Ken Gerhart, Keith Hughes, Fred Lynn, Joe Orsulak, Pete Stanicek, Jim Dwyer, and two unknown signatures