Lewis is best known for his career as a Raven, where he helped the team win Super Bowl XXXV as a rookie. Lewis is also known for his outstanding 2003 season, where he rushed for 2,066 yards, which is third-most of all-time, behind Eric Dickerson and Adrian Peterson. That same year, Lewis also rushed for 295 yards in one game, which was the single-game record until Adrian Peterson rushed for 296 yards in 2007. Lewis was inducted into the Ravens' Ring of Honor on September 27, 2012.

This Baltimore Ravens Pro Line helmet was signed in gold by Lewis and inscribed, "Single Game Rushing Record 295 YDS. 9-14-03." This helmet includes a JSA sticker and COA.