The Baltimore Ravens selected Boulware in the first round, with the fourth overall pick in the 1997 NFL Draft. In 1997 Boulware recorded 66 total tackles, 11.5 sacks, and one forced fumble to receive the NFL Defensive Rookie of the Year by the Associated Press. He would play for the Ravens for eight years, going to four Pro Bowls and becoming the Ravens' all-time sack leader, a title he held until he was surpassed by Terrell Suggs in 2011. Boulware was also a member of the Baltimore Ravens' Super Bowl-winning team during the 2000 NFL season. Boulware finished his career with 493 tackles, a franchise record 70 sacks, 26.5 tackles for losses, 13 forced fumbles, 5 fumble recoveries, 19 pass deflections, and 1 interception for six yards in 126 career games.

This 2003 Baltimore Ravens game issued jersey was signed by Peter Boulware and includes an NFL Auction - PSA/DNA sticker.