After only five batters, the National League owned a 3–0 lead. Willie Mays hit a leadoff home run to left field off Milt Pappas, followed by a Willie Stargell single and a two-run Joe Torre homer. Stargell's two-run homer in the second inning off Mudcat Grant made it 5–0. The NL was coasting until a four-run fifth inning against Jim Maloney, which included a pair of two-run homers by Dick McAuliffe and Harmon Killebrew, tying the game at 5-all. The winning run scored in the seventh versus Sam McDowell on a walk to Mays, single by Hank Aaron, ground out by Roberto Clemente and infield hit by Ron Santo. Saving the game for the NL with two innings of relief was Bob Gibson, who, with Tony Oliva in scoring position after a ninth-inning double, struck out Killebrew and Joe Pepitone to end the game. National League starting pitcher Juan Marichal was named MVP.

This 1965 All-Star Game program has some wear to the cover but no rips or creases. The program is unscored. Also included is a ticket stub to the game, which has been ripped and has a crease from being folded.