After 6 years with the Indianapolis Colts, Siragusa signed with the Baltimore Ravens in 1997. He was a part of the 2000 Baltimore Ravens defense that allowed the fewest total points in NFL history for a 16-game season.

Siragusa was fined $10,000 for an illegal hit on Oakland Raiders QB Rich Gannon in the 2000 AFC title game, injuring Gannon’s shoulder. He helped lead the Ravens to their first Super Bowl in franchise history in Super Bowl XXXV where they beat the New York Giants, 34-7.

Siragusa retired following the 2001 season. He finished his career with 562 tackles, 22 sacks, five forced fumbles, nine fumble recoveries for 12 yards, and 28 pass deflections in 170 career games.