Throughout his career, Thome's strength was power hitting. In six different seasons, he hit more than 40 home runs, and in 2003, he led the National League in home runs with 47. His career OPS of .956 is 19th all time. In 2011, he became the eighth MLB player to hit 600 home runs. As of 2017 Thome is the career leader in walk-off home runs with 13. One of Thome's trademarks was his unique batting stance, in which he held the bat out with his right hand and pointed it at right field before the pitcher threw, something he first saw in The Natural. Thome was known for his consistently positive attitude and "gregarious" personality. An active philanthropist during his playing career, he was honored with two Marvin Miller Man of the Year Awards and a Lou Gehrig Memorial Award for his community involvement.
This Philadelphia Phillies replica batting helmet was signed on the brim by Thome and includes a Beckett sticker and COA.