Dilfer signed with the Ravens on March 8, 2000 and became the backup for Tony Banks. After two straight losses and four straight weeks without an offensive touchdown, the Ravens replaced Banks with Dilfer. The Ravens would lose their third straight game and fail to score a touchdown for the fifth straight week. It would be the last time the Ravens would lose a game that season, or go without a touchdown. The Ravens finished the season winning seven straight to earn a wild card berth at 12-4. The 7-1 run also gave Dilfer a 45-39 record as a starter at that point.

In the playoffs, Dilfer went 3-0, and the Ravens advanced to Super Bowl XXXV in Tampa, Florida to meet the New York Giants. Halfway through the first quarter he connected with Brandon Stokley on a deep post for a 38-yard touchdown, badly beating Jason Sehorn. A third down 44-yard pass to Qadry Ismail would set up a field goal before halftime, to give Baltimore a 10-0 lead. The Ravens eventually won 34-7.

This Wilson official Super Bowl XXXV football was signed in silver by Dilfer and inscribed "Ravens 34, Giants 7." This item includes a Great Moments COA.